With buzz building across the globe, the momentum is sure to continue into 2019, when the combined North American market is expected to exceed $16 billion.
A depiction of a cannabis bud drops from the ceiling at Leafly’s in Toronto, as midnight passes and marks the first day of the legalization of cannabis across Canada on Oct. 17, 2018.Chris Young / AP
PORTLAND, Ore. — The last year was a 12-month champagne toast for the legal marijuana industry as the global market exploded and cannabis pushed its way further into the financial and cultural mainstream.
Liberal California became the largest legal U.S. marketplace, while conservative Utah and Oklahoma embraced medical marijuana. Canada ushered in broad legalization, and Mexico’s Supreme Court set the stage for that country to follow.
U.S. drug regulators approved the first marijuana-based pharmaceutical to treat kids with a form of epilepsy, and billions of investment dollars poured into cannabis companies. Even main street brands like Coca-Cola said they are considering joining the party.
“I have been working on this for decades, and this was the year that the movement crested,” said U.S. Rep. Earl Blumenauer, an Oregon Democrat working to overturn the federal ban on pot. “It’s clear that this is all coming to a head.”
With buzz building across the globe, the momentum will continue into 2019.
Luxembourg is poised to become the first European country to legalize recreational marijuana, and South Africa is moving in that direction. Thailand legalized medicinal use of marijuana on Tuesday, and other Southeastern Asian countries may follow South Korea’s lead in legalizing cannabidiol, or CBD. It’s a non-psychoactive compound found in marijuana and hemp plants and used for treatment of certain medical problems.
“It’s not just the U.S. now. It’s spreading,” said Ben Curren, CEO of Green Bits, a San Jose, California, company that develops software for marijuana retailers and businesses.
Curren’s firm is one of many that blossomed as the industry grew. He started the company in 2014 with two friends. Now, he has 85 employees, and the company’s software processes $2.5 billion in sales transactions a year for more than 1,000 U.S. retail stores and dispensaries.
Green Bits raised $17 million in April, pulling in money from investment firms including Snoop Dogg’s Casa Verde Capital. Curren hopes to expand internationally by 2020.
“A lot of the problem is keeping up with growth,” he said.
Legal marijuana was a $10.4 billion industry in the U.S. in 2018 with a quarter-million jobs devoted just to the handling of marijuana plants, said Beau Whitney, vice president and senior economist at New Frontier Data, a leading cannabis market research and data analysis firm. There are many other jobs that don’t involve direct work with the plants but they are harder to quantify, Whitney said.
Investors poured $10 billion into cannabis in North America in 2018, twice what was invested in the last three years combined, he said, and the combined North American market is expected to reach more than $16 billion in 2019.
“Investors are getting much savvier when it comes to this space because even just a couple of years ago, you’d throw money at it and hope that something would stick,” he said. “But now investors are much more discerning.”
Increasingly, U.S. lawmakers see that success and want it for their states.
Nearly two-thirds of U.S. states now have legalized some form of medical marijuana.
Voters in November made Michigan the 10th state — and first in the Midwest — to legalize recreational marijuana. Governors in New Yorkand New Jersey are pushing for a similar law in their states next year, and momentum for broad legalization is building in Pennsylvania and Illinois.
“Let’s legalize the adult use of recreational marijuana once and for all,” New York Gov. Andrew Cuomo said last week.
State lawmakers in Nebraska just formed a campaign committee to put a medical cannabis initiative to voters in 2020. Nebraska shares a border with Colorado, one of the first two states to legalize recreational marijuana, and Iowa, which recently started a limited medical marijuana program.
“Attitudes have been rapidly evolving and changing. I know that my attitude toward it has also changed,” said Nebraska state Sen. Adam Morfeld, a Democrat. “Seeing the medical benefits and seeing other states implement it … has convinced me that it’s not the dangerous drug it’s made out to be.”
With all its success, the U.S. marijuana industry continues to be undercut by a robust black market and federal law that treats marijuana as a controlled substance like heroin. Financial institutions are skittish about cannabis businesses, even in U.S. states where they are legal, and investors until recently have been reluctant to put their money behind pot.
Marijuana businesses can’t deduct their business expenses on their federal taxes and face huge challenges getting insurance and finding real estate for their brick-and-mortar operations.
“Until you have complete federal legalization, you’re going to be living with that structure,” said Marc Press, a New Jersey attorney who advises cannabis businesses.
Brokaw’s legendary probity makes his public admission a landmark in erasing marijuana’s fading stigma.
Add Tom Brokaw to the growing number of public celebrities embracing medical marijuana. Long an American symbol of stalwart and at times fussy newsmen, Brokaw is in remission from multiple myeloma (a cancer that grows in bone marrow). However, the pain sustained in his bones from the cancer has turned Brokaw to medical marijuana.
“I’m now on medical marijuana for my back, for the first time,” Brokaw told SurvivorNet, a cancer information site. “I’ve not done that before.”
Brokaw admits that he’s no less ambitious a journalist and currently working on a book about Richard Nixon. “Politics keep me distracted from cancer,” he says. But when he’s not working on that, trying to acquire medical marijuana in Florida, where he resides, is “complicated” and almost a full-time job in itself.
In coming out as a marijuana advocate, Brokaw engenders himself to a growing number of cancer patients using medical marijuana in treatment. According to SurvivorNet’s CEO Steve Alperin, more people are trying to learn more about medical marijuana and having someone like Brokaw open up about his experience will “help people understand there are alternative approaches to pain management.”
That said, Brokaw says he’s “keenly aware” how fortunate his cancer battle has been. When he was diagnosed with multiple myeloma back in August 2013, he was immediately medevacked to the Mayo Clinic with a room already available for him. He went through years of treatment — including chemotherapy and spinal operations — but all that cost tons of money.
“An extraordinary amount of progress has been made with drugs and treatment. We haven’t gotten the cost thing worked out yet,” he told SurvivorNetOpens a New Window.. “At one point, I counted up the price and it was something like $10,000 a day, you know, that I was spending on drugs. I have the blessing of having a great program through first RCA, then GE, and now Comcast. So the checks that I write for pharmacy are very, very small. And it makes — every time I do that, it makes me aware of the people who are not in the same position that I am, and how I think about them.”
How ineffective are current Alzheimer’s disease treatments? Quite. So much so, in fact, that David Cameron, the Conservative former prime minister of the United Kingdom – a supposed BFF of Big Business and one can only deduce, Big Pharma – called out the pharmaceutical industry for its “failures undermining dementia research and drug development.” A huge multi-billion-dollar industry being called out by a world leader isn’t something that happens every day.
But then again, Cameron’s sentiments have plenty of merits. Per Scientific American, dementia drug research has failed miserably. In a mega-study investigating 244 drugs across 413 clinical trials, researchers found that just one drug was approved. In other words, 99.6 percent of the experiments amounted to nothing. Just this past January, another company discontinued not one but two Alzheimer’s drugs during the final stages of clinical trials.
So, what is going on? Well, it’s one thing for a politician to lambast an industry for their lack of progress and next-to-nil results; it’s quite another to pinpoint and act upon the catalysts of dementia. It certainly doesn’t help that the drug industry is so entrenched into the health care apparatus either, as this discourages looking at alternative methods of care. Mix in public ignorance about natural remedies (yes, including marijuana) and the outlook doesn’t appear favorable.
But researchers may just be edging ever closer to a real solution to the Alzheimer’s problem – and it isn’t in the form of an expensive pill. What is it, then? Well, if studies are to be believed, it’s the use of cannabis.
In this article, we’re going to discuss some interesting findings concerning the use of cannabis and Alzheimer’s disease. We’ll briefly touch on the problem of Alzheimer’s in today’s society as well as the problems posed by conventional dementia treatments.
ALZHEIMER’S DISEASE: AN OVERVIEW
Alzheimer’s disease is a progressive neurodegenerative disease characterized by a gradual loss of memory, learning ability, communication, and judgment. In some cases, these cognitive functions decline to a point where the person becomes entirely dependent on caregivers for daily activities.
Alzheimer’s is typically found in those over the age of 65, of whom approximately 1 in 14 adults are affected. The highest concentration of patients with the disease are those over the age of 80, with 1 in every 6 meeting the criteria for diagnosis. This type of Alzheimer’s, also known as Late-onset Alzheimer’s is the most common, accounting for nearly 90 percent of all cases.
Only 6 to 8 percent of patients develop symptoms before the age of 65 – a condition known as early-onset Alzheimers – with those affected having a family history of the disease.
The rarest form of Alzheimer’s is called Familial Alzheimer’s disease (FAD), which is believed to be wholly inherited. In affected families, members of at least two generations are found to have had Alzheimer’s disease. FAD accounts for less than 1 percent of all Alzheimer’s cases.
Alzheimer’s disease symptoms are classified into three categories: mild, moderate, and severe.
COMMON SYMPTOMS OF MILD ALZHEIMER’S INCLUDE:
Difficulty completely once-routine tasks
Impaired sense of judgment
Impaired sense of direction or getting lost
Increased anxiety and aggression
Lethargy and lack of purpose
Memory loss
Monetary difficulties
Poor decision making
Repeating the same questions
MODERATE SYMPTOMS INCLUDE:
All of the symptoms mentioned above
Further deterioration of memory
Poor judgment and worsening confusion
Requiring assistance when doing simple tasks (e.g. bathing, grooming, using the bathroom.)
Significant changes in personality and behavior.
SEVERE SYMPTOMS MAY INCLUDE:
All of the signs mentioned above
Losing the ability to converse or speak
Complete dependence on others for many tasks
Declining physical abilities (e.g. inability to walk or sit up straight, rigid muscles, etc.)
PROBLEMS ABOUND WITH DEMENTIA DRUGS
It’s not just that so few drugs are approved for Alzheimer’s and other forms of dementia; the problem is also that they are ineffective and downright counterproductive in just about every conceivable way. Let us briefly discuss the problems with current dementia treatment.
1. THEY’RE EXPENSIVE
First, Alzheimer’s prescription drugs are costly. While Medicaid covers much of the costs, prescription drugs for dementia can add up to hundreds of dollars per month. For seniors who live on a fixed income, this amount may be unattainable, forcing them to choose drugs over other necessities like food, or vice-versa.
2. THEY CARRY NASTY SIDE EFFECTS
Among the pervasive side effects of dementia medicines are abdominal cramps, bruising, confusion, constipation diarrhea, insomnia, muscle cramps, nausea, vomiting, fatigue, and weight loss.
3. THEY’RE INEFFECTIVE (EXCEPT FOR ONE)
While the statistics may vary, they seem to agree on this point: Alzheimer’s prescription medications aren’t very effective at doing what they say they’ll do. In a meta-analysis of 41 randomized control trials published in Alzheimer’s Research & Therapy, the research team concludes that there is not one drug that reduces neuropsychiatric symptoms of Alzheimer’s.
Memantine is the sole dementia medication that carries significant benefits. In both the previous meta-analysis, and the second analysis of 30 studies published in the Journal of Alzheimer’s Disease, memantine (brand name “Namenda”) significantly improved learning, cognition, and memory. (Furthermore, compared with the other type of dementia medications – acetylcholinesterase inhibitors [e.g. donepezil] – memantine has relatively few and less severe side effects.)
CANNABIS AS AN ALZHEIMER’S AND DEMENTIA TREATMENT
“When we investigated the power of THC … we found that [it] was a very effective inhibitor of acetylcholinesterase. [We] also found that THC was considerably more effective than two of the approved drugs…” – Kim Janda, Ph.D. (source)
It’s a good thing that marijuana use is becoming less and less taboo – especially for those with medical conditions. To give you an idea of just how widespread cannabis is as either a primary or secondary treatment option, consider what it’s been thought to help treat:
Alzheimer’s disease (of course!)
Anxiety
Cancer (by killing cancer cells and slowing tumor growth)
Chron’s disease
Chronic pain
Eating disorders
Epilepsy
Excessive weight loss (in people with AIDS and cancer)
Glaucoma
Inflammation
Loss of appetite
Mental health conditions such as schizophrenia and posttraumatic stress disorder (PTSD)
Nausea and vomiting (from chemotherapy)
Multiple sclerosis (MS)
Muscle spasms
UNDERSTANDING ALZHEIMER’S
To understand how cannabis may help treat Alzheimer’s, we must first understand the underlying neurophysiology of the disease. To this point, researchers attribute the onset and progression of the disease to the buildup of a sticky plaque protein called beta-amyloid. It is thought that the protein disrupts communication between neurons in the brain and causes cellular death. It is these effects of the beta-amyloid, neuroscientists say, that causes both the cognitive and neuropsychiatric problems seen in Alzheimer’s patients.
An active compound in marijuana called tetrahydrocannabinol (THC) may help to remove the toxic buildup of beta-amyloid, say researchers from the Salk Institute for Biological Studies in California. Moreover, THC may also help to reduce inflammation in nerve cells. Dave Schubert, the leading neurobiologist at the institute, believes that his team’s study is the first of its kind to demonstrate these dual properties of THC.
Schubert’s team may have made another novel finding: the inflammation produced in the brain may stem from beta-amyloid buildup within the neurons – not immune-like cells within the brain as thought previously. Moreover, “THC-like compounds (within) the nerve cells themselves may be involved in protecting the cells from dying,” says Antonio Currais, a researcher in Shubert’s lab.
Schubert’s team attributes these the anti-inflammatory, beta-amyloid reduction properties to THC to activation of the brain’s “switches,” or receptors. Research has shown that endocannabinoids activate these receptors, causing intracellular signaling within the brain. As THC has similar molecular activity as endocannabinoids, they have similar effects of the brain’s receptors.
FINAL THOUGHTS
In related research, Schubert’s lab discovered that a potential drug known as J147 produces similar effects of beta-amyloid proteins and reduces the inflammatory response in the brain. Schubert’s team has found that the J147 drug works by manipulating a mitochondrial protein called ATP, which performs the role of providing cellular energy to neurons. As of this writing, J147 is said to be nearing clinical trials – the first step, albeit a long one, in gaining approval for mass manufacturing and distribution.
As of this writing, the Salk Institute is advancing its research on THC and endocannabinoids as a potential Alzheimer’s treatment.
High THC Cannabis Oil has been used by numerous people for centuries, but it was banned in the second half of the 20th century, as a result of the rise of the billion-dollar pharmaceutical industry.
Mike Wise is a retired professional skateboarder and national champion athlete with The University of Texas where he graduated with a degree in Radio-Television-Film in 2009. He has never been a fan of doctors, so when he got diagnosed with Crohn’s disease in 2014 he decided to take his health into his own hands.
Nowadays, he is one of the most well known activists in the world fighting for the legalization of cannabis oil. Using this treatment, he has cured over 2,000 people from a variety of diseases including terminal ones such as Cancer and Glioblastoma (brain tumors).
Since moving to Europe in 2017, he has spoken at over 30 different countries all over the world on this topic. He is also currently filming a documentary with Rick Simpson to tell his story and help to get this information out to the public.
He states that cannabis oil can cure a vast variety of serious health issues, like diabetes, arteriosclerosis, multiple sclerosis, epilepsy, asthma, psoriasis, as well as some of the deadliest forms of cancer.
Mike recently recounted his story to a magazine in the Czech Republic: “I always tell people – Cannabis will cure you, and you will see that at present, it is the best cure there is in the world!”
He began his story: “It was 2014. I had been dealing with symptoms related to Crohn’s disease since 2000. As an athlete, I was always busy traveling and competing. Doing so caused much damage to build up in my body after years of this abuse. The symptoms got worse and worse until I began vomiting blood every morning at 4am when I would wake up, and several times throughout the day; every day.
I had been studying plants as a hobby for years, and had been growing cannabis illegally since 2005 to smoke and occasionally make into edibles. After moving to Colorado in 2014, I began to learn a lot more about growing from other local growers and about cannabis as a medication from other local activists, caregivers, and enlightened doctors. I was filming a movie about families who had to move and relocate from another state to access medical cannabis in Colorado for their children entitled: ‘Illegally Alive’, which you can watch for free with this link. www.youtube.com/watch?v=OOn142GAjsU
During the production of the film, I got in touch with Rick Simpson and flew out to Zagreb, Croatia to interview with him in person. While I was out there, we attended a conference in Ljubljana, Slovenia where Rick was speaking. I had to run outside in the middle of the conference to vomit. Rick saw me and said: ‘Mike, you really need to get on this oil brother’.
After getting the kick in the butt I needed from the godfather of cannabis oil himself, I ingested 90 grams in 120 days of high THC oil and cured all my symptoms relating to Crohn’s disease. This first 45 grams I ingested orally, the second 45 grams I took via suppository. Now I only take 1 gram per month as a maintenance dose.
It’s important to note that I never elected to undergo any surgeries. I did not let the doctors mutilate me and remove any organs or other body parts. I also completely changed my diet eliminating all processed foods, sugars, and carbohydrates. If I ingest any of these substances, I will need to take oil to prevent any new symptoms from showing up. I also eliminated as many sources of stress from my life I possibly could.
After curing myself, I decided to share my story publicly on social media. I immediately began to receive hundreds of messages a week from friends and acquaintances of friends. Everybody needed cannabis oil for their brother, mother, sister, daughter, father, grandmother, grandfather, etc…
I decided to get my Caregiver License in Colorado and immediately planted 500 seeds in my basement and began to supply the oil to anyone who asked. I have never turned anyone away since I started making the oil for myself and others started asking for it. I even used to make it for free. I would tell patients if they could bring me the materials and solvent needed to make the oil, then I would make it for them for free and would not charge them for my time or labor.
To take my activism a step further, I created an activist run and oriented company called: ‘OG Labs’. On my website (www.oglabsgenetics.com/oil.html) anybody in the world can now reach me and have the oil made and sent discreetly to their doorstep to any state or country in the world. I believe, as the great Thomas Jefferson did, that ‘if a law is unjust, a man is not only right to disobey it, he is obligated to do so.’ I am hoping that by openly offering the oil for sale publicly, that other activists around the world will see what I am doing and feel empowered to stand up and make the oil for patients in need as well.”
Cannabis oil therapy is equally effective in all cases, for it knows no age limit. It can even be given to babies. People who publicly claim to cure cancer are threatened with 5 – 40 years imprisonment, according to laws in North America. Mike says the preparation of this miraculous oil is extremely easy. The standard protocol starts with several drops of cannabis oil three times a day.
“The usual dose I start cancer patients on is 60 grams within 90 days. If the patient has undergone any chemotherapy or radiation they will need much more than 60 grams”, he explains.
“Cannabis is not a miracle drug in the sense that most people think. The cannabis itself doesn’t necessarily cure you; your body heals and cures itself. Cannabis simply triggers this reaction to occur. You see, cannabis works like a key inserted into a lock. Your bodies contain what is known scientifically as CB1 and CB2 receptors spread throughout it’s entire system and on every organ. When cannabis gets into the body and into these CB1 and CB2 receptors it works like a key opening a lock, the receptors then began firing correctly and any imperfections or illnesses which are contained within your body will immediately begin to get healed because these receptors are literally located everywhere within your body.”
“This is significant for 2
reasons,” he continues “cannabis can help to heal or cure nearly any illness or
disease because these receptors send signs to your body and organs to begin functioning
correctly and to stop misfiring. In the case of cancer, these receptors will
tell the body how to identify cancer cells and can help to specifically target
and kill them without the use of any harmful or invasive treatments.
The second reason this is important is regarding chemotherapy and radiation specifically. I personally believe that these treatments do more harm than good. There are numerous studies out there stating that more people die from cancer treatments than from the cancer itself. To put it plainly, chemotherapy kills more people than it heals. After treating so many patients with cannabis oil, I began to notice a pattern. Patients who have taken chemotherapy or radiation always require more oil than the standard 60 grams in 90 days.
I know some patients who have taken dozens of chemo sessions, and have now consumed over 350+ grams of oil. They have consumed a lot of oil, and continue to take it today; but they are still alive. They often come to me after the doctors have given up on them, with only weeks to live. Their bodies are extremely frail and damaged. I believe that this is from the chemotherapy.
It is not a targeted treatment. It kills all cells in your body, unlike THC cannabis oil which helps to identify and kill only the cancer cells. This is why patients who are diagnosed with cancer and have not done any chemotherapy or radiation typically need 60 grams in 90 days before switching to a maintenance dose, as opposed to those who have done chemotherapy or radiation. They need more oil because their bodies are far more damaged from both the cancer, and the chemotherapy; as opposed to being damaged by just the cancer itself. Your body needs more oil, and more time to rest and heal from all the damage incurred.”
And, it is never too late for the patient to start cannabis oil therapy. He believes that every country in the world should allow their citizens to cultivate and use cannabis for medical purposes. He also points out that pharmacies should be opened for those who can’t cultivate it if they can supply it at fair rate for all people, not just the rich.
“Little is known that cannabis has been used as one of the most
healing remedies for hundreds of years before Christ.
In the ancient Persian religious scripts, which among other
things describe the most healing herbs, cannabis takes the first place,”
concludes Mike.
His biggest wish and goal is to live in a world without cancer
where every person can legally cultivate as many cannabis plants as they would
like on their property or in their home, and where every person in the world
can legally and openly consume cannabis (like smoking it) in every place where
you can legally smoke tobacco or cigarettes. Until that day comes he tells us
that he will continue fighting for our rights to do so.
If you have access to materials and would like to watch his detailed video on how to make it yourself, you can do so here: www.youtube.com/watch?v=SKT9tRcA-RU
He also hosts a page completely dedicated to cannabis patients on YouTube which can be found here: www.youtube.com/TheMikeWiseShow
Below is a video of Dr. Christina Sanchez, a molecular biologist at Compultense University in Madrid, Spain, clearly explaining how THC (the main psychoactive constitute of the cannabis plant) completely kills cancer cells.
Cannabinoids refer to any group of related compounds that include cannabinol and the active constituents of cannabis. They activate cannabinoid receptors in the body. The body itself produces compounds called endocannabinoids and they play a role in many processes within the body that help to create a healthy environment. I think it’s also important to note that cannabis has been shown to treat cancer without any psychoactive effects.
Cannabinoids have been proven to reduce cancer cells as they have a great impact on the rebuilding of the immune system. Although not every strain of cannabis has the same effect, more and more patients are seeing success in cancer reduction in a short period of time by using cannabis. Contrary to popular belief, smoking cannabis does not assist a great deal in treating disease within the body as therapeutic levels cannot be reached through smoking. Creating oil from the plant or eating the plant is the best way to go about getting the necessary ingredients, the cannabinoids.
The world has come a long way with regards to accepting this plant as a medicine rather than a harmful substance. It’s a plant that could benefit the planet in more ways than one. Cannabis is not something offered in the same regard as chemotherapy, but more people are becoming aware if it, which is why it’s so important to continue to spread information like this. Nobody can really deny the tremendous healing power of this plant.
At 10 months of age, Kalel Santiago of Puerto Rico was diagnosed with a rare form of cancer called neuroblastoma. He endured chemotherapy, radiation treatments, and surgery for two years—and survived. Then he was diagnosed with something permanent: severe autism that disabled him from speaking.
“While he was in the hospital, we noticed he didn’t speak at all and had some behavior that wasn’t right, like hand flapping, and walking on his toes,” his father Abiel Gomez Santiago told Yahoo News. “But we waited until he was 3 and cancer-free to look at his behavior.”
According to Yahoo, “He and his wife Gladys — also parents to two older boys, now 18 and 20 — did a cram course in educating themselves on autism. They tried various schools and therapies and eventually found impressive success with a unique surf-therapy school near their home.”
Eventually, the Santiago family stumbled upon a treatment of real potency and potential: CBD oil.
Through a fundraising program, they were able to receive a tiny bottle of the oil. Kalel was given oral doses twice a day.
Within just two days, he was finally able to speak. “He surprised us in school by saying the vowels, A-E-I-O-U. It was the first time ever,” Abiel said. “You can’t imagine the emotion we had, hearing Kalel’s voice for the first time. It was amazing. The teacher recorded him and sent it to my wife and me and we said well, the only different thing we have been doing is using the CBD.”
Soon after, he began using consonants, too, speaking like his parents never thought possible. “He said, ‘amo mi mama,’ ‘I love my mom,’” Abiel says. “I don’t know how to thank [the CBD oil makers].”
Kalel’s story is yet another piece of evidence piling onto the mountain of support for cannabis oil and full marijuana legalization. Please share this with as many people as possible.
Originally published September 28, 2018 at http://yourhealthdoc.com/autistic-boy-gains-ability-to-speak-after-just-2-days-of-cannabis-oil-treatment-3/?fbclid=IwAR2GwbvayI5NzVBMgdjmfVCJvFAzGCbOn6bAt-5g9POSSKJ4LvYTYLRryrA
A group including 12 former heads of state has called for drugs to be legalized worldwide, as the war on drugs has ‘failed’, a report published today said.
The report ‘Regulation: The Responsible Control of Drugs’ by the Global Commission on Drug Policy found that arresting drug dealers has had little effect.
Instead, governments should introduce regulated markets for drugs – and turn away from global policies which require prohibition and punishment. Should weed be legalised worldwide?
‘The international drug control system is clearly failing,’ said Helen Clark, a former prime minister of New Zealand.
‘The health … of nations is not advanced by the current approach to drug control.’
‘Current drug policies are reducing neither the demand nor the supply of illegal drugs, quite the contrary, while the increasing power of organized crime is a sad reality,’ writes Ruth Driefuss, the former president of Switzerland and chair of the commission.
By taking control of illegal drug markets, the report argues governments can weaken the powerful criminal gangs that have grown despite decades of efforts to stamp them out. Cesar Gaviria, former president of Colombia Source: Bloomberg Mexico’s President-elect Andres Manuel Lopez Obrador
The commission chose to launch its report in Mexico, whose criminal gangs are top suppliers of heroin, methamphetamine, cocaine and marijuana to the United States and where gang-related violence has driven murders to a record high.
‘Mexico is the most important country in the fight against drugs,’ said former Colombian president Cesar Gaviria.
Mexico’s recent history exemplifies the report’s claim that evidence shows arresting drug traffickers has little impact on drug supply and may increase violence. Should drugs be legalised? Yes No Yes, but only soft drugs like weed
Just over 10 years ago, Mexico intensified its battle with drug gangs by sending out the military to battle traffickers.
While dozens of kingpins have been captured or killed, the number of gangs operating in Mexico has multiplied as new criminal leaders step into the breach and battle over turf.
The commission recommends governments open participatory processes to shape reforms toward regulation.
Incoming Mexican President-elect Andres Manuel Lopez Obrador has already started to hold town-hall reviews on violence and discuss potential ‘amnesty’ for non-violent drug traffickers and farmers. Members of his team have said Mexico will evaluate creating legal markets for marijuana as well as opium.
The report calls for a renegotiation of the international treaties that created a ‘repressive’ strategy where drug users and low-level dealers face stiff prison sentences, but it cautions nations are far from a global consensus yet.
Originally published by: Rob Waugh Monday 24 Sep 2018 8:39 am at https://metro.co.uk/2018/09/24/former-world-leaders-call-for-worldwide-legalisation-as-war-on-drugs-has-failed-7973392/
Dr. Lee Cowden says most people don’t die from cancer; they die from the side effects of treatment. While the “war against cancer” is moving toward more personalized and so-called “precision medicine” treatments, the old standby model of “cut, poison and burn,” via surgery, chemotherapy and radiation, is still widely used and regarded as the standard of care for many cancer cases.
One of the major problems with chemotherapy is its indiscriminate toxicity, which poisons your body systemically in an attempt to knock out cancer cells. There have long been signs that this model has fatal flaws and may cause more harm than good. In the case of the breast cancer chemotherapy drug Tamoxifen, for instance, patients must trade one risk for another, as while it may reduce breast cancer, it more than doubles women’s risk of uterine cancer.1
Serious, sometimes-fatal side effects (or more aptly, simply effects) of chemotherapy are common, as are serious unforeseen effects that may make your cancer prognosis worse instead of better.
Writing in the journal Science Translational Medicine, researchers from the Albert Einstein College of Medicine revealed that giving chemotherapy prior to surgery for breast cancer may promote disease metastasis, or the growth and spread of cancer to other areas of the body.2 This, in turn, greatly increases a woman’s risk of dying from the disease.
Chemotherapy May Make Breast Cancer More Aggressive and Likely to Spread
Preoperative chemotherapy, known as neoadjuvant chemotherapy, is often offered to women because it may help shrink tumors, which increases the likelihood that women will receive lumpectomy surgery instead of a full mastectomy. After performing tests on mice and human tissue, however, the researchers found that doing so may increase the likelihood of metastasis by increasing what are known as “tumor microenvironments of metastasis.” As Stat News explained:3
“Called ‘tumor microenvironments of metastasis,’ these on-ramps are sites on blood vessels that special immune cells flock to. If the immune cells hook up with a tumor cell, they usher it into a blood vessel like a Lyft picking up a passenger. Since blood vessels are the highways to distant organs, the result is metastasis, or the spread of cancer to far-flung sites.”
When mice with breast cancer or given human breast tumors were given the chemotherapy, it altered the tumor microenvironment in ways that made them more conducive to cancer spread, including, Stat reported:4
Increasing the number of immune cells that transport cancer cells into blood vessels
Making blood vessels more permeable to cancer cells
Making tumor cells more mobile
In mice, chemotherapy treatment doubled the number of cancer cells in the bloodstream and lungs compared to mice that did not receive the treatment. Further, in 20 human patients who received common chemotherapy drugs, the tumor microenvironments also became more favorable to cancer spread. As The Telegraph noted:
“It is thought the toxic medication switches on a repair mechanism in the body which ultimately allows tumors to grow back stronger. It also increases the number of ‘doorways’ on blood vessels which allow cancer to spread throughout the body.”5
Further, researchers wrote in a 2012 Journal of Clinical Oncology editorial, “Unfortunately, neoadjuvant chemotherapy does not seem to improve overall survival, as demonstrated in the National Surgical Adjuvant Breast and Bowel Project (NSABP) B18 trial, among others.”6 This means women may be trading a potential increased risk of cancer metastasis for a treatment that doesn’t even improve their chances of survival.
It’s Been Known for Years That Chemotherapy Can Trigger Tumor Growth
While the news that chemotherapy may encourage cancer spread may sound surprising, it’s not a new discovery. In 2012, researchers found chemotherapy for prostate cancer caused DNA damage in healthy cells and caused them to secrete more of a protein called WNT16B, which boosts tumor growth and may encourage cancer cells to develop resistance to treatment.
“WNT16B, when secreted, would interact with nearby tumor cells and cause them to grow, invade and, importantly, resist subsequent therapy,” study co-author Dr. Peter Nelson, of the Fred Hutchinson Cancer Research Center, told AFP News.7
In the journal Nature Medicine, the researchers further noted, “The expression of WNT16B in the prostate tumor microenvironment attenuated the effects of cytotoxic chemotherapy in vivo, promoting tumor cell survival and disease progression”8 and “ … [D]amage responses in benign cells … may directly contribute to enhanced tumor growth kinetics.”9
While research continues to reveal that chemotherapy’s effects are wide-reaching and devastating to healthy cells, it’s also been shown — at least as far back as 2004 — that “chemotherapy only makes a minor contribution to cancer survival.”10 A Clinical Oncology study found that in terms of five-year survival rates in adult cancer cases, chemotherapy has an average five-year survival success rate of just 2.3 percent in Australia and 2.1 percent in the U.S.11
Separate research revealed that out of nearly 2,000 patients receiving chemotherapy, 161 deaths occurred within 30 days of the treatment. Nearly 8 percent of them were classified as related to the chemotherapy (and another nearly 16 percent were unclassified due to insufficient information).12
Further, as mentioned, chemotherapy can increase the risk of subsequent cancer, such as therapy-related acute myeloid leukemia (tAML), “a rare but highly fatal complication of cytotoxic chemotherapy.” Researchers noted that tAML cases occur nearly five times more often in adults treated with chemotherapy than they do in the general population.13
Conventional Oncologists Aren’t Likely to Explain the Many Options for Treatment
Upon receiving a cancer diagnosis, many people assume their only options for treatment are chemotherapy, surgery or radiation. Only you and your health care team can make the decision on how to best pursue treatment, but you should know that conventional providers are unlikely to think outside the box.
Oncology is the only specialty in medicine that is allowed and even encouraged to sell drugs at massive profits — typically in excess of 50 percent — and cancer drugs are, as a general category, the most expensive medications in all of medicine to begin with. Oncologists actually get a commission for the chemotherapy drugs they sell, and with that type of incentive, it’s nearly impossible to imagine them actively seeking other alternatives.
Oncologists are further constrained by the “standard of care” prescribed by oncology medical boards and the drug industry. If they go against the established standard of care, they’re susceptible to having their license reprimanded or even taken away. As a result, patients are typically forced to go it alone if they don’t want to go the conventional route, which is unfortunate because there are many promising alternative treatments.
Understanding Your Options for Cancer Treatment
A comprehensive natural cancer-fighting approach would be to make your body as healthy as possible, using detoxification, strategies to boost your immune function, dietary changes and other targeted therapies depending on your needs. For instance, Annie Brandt — a 16-year cancer survivor and author of “The Healing Platform: Build Your Own Cure!” — states products that are helpful against metastatic cancer cells include:
The point is that there are many anti-cancer strategies overlooked by conventional medicine. Many of them even work in addition to conventional treatment. For instance, vitamin C in combination with nutritional ketosis and fasting prior to administering chemotherapy radically improve the effectiveness of chemotherapy.
Oncologists in Turkey, who aren’t under the same U.S. restrictions, are also using a stacked ketogenic treatment protocol that is showing shocking remissions in many stage 4 cancer patients. The treatment protocol at ChemoThermia Oncology Center in Turkey includes:
At the center, all oncology patients are put on a ketogenic diet, which creates metabolic stress on the cancer cells. Then, prior to administering the chemo, the patient will do a 14-hour fast, which further increases the metabolic stress on the cancer cells.
The patients will typically have a blood glucose level around 80 milligrams per deciliter (mg/dL) at this point. They then apply glycolysis inhibitors to inhibit the glycolysis pathway in the cancer cells, which creates a terrific amount of metabolic stress, as the cancer cells are already starved of glucose.
Insulin is then applied to lower the blood glucose levels to around 50 or 60 mg/dL, to cause mild hypoglycemia. At that point, chemotherapy is applied, often at a far lower dose than would otherwise be used, thereby lowering the risk of side effects.
In the days following chemotherapy, hyperthermia and hyperbaric oxygen therapy are applied, plus a daily infusion of glycolysis inhibitor therapies with high-dose vitamin C (50 grams) and dimethyl sulfoxide (DMSO). A sampling of other targeted therapies covered in Brandt’s book are below.
Poly-MVA, a colloidal mineral complex that crosses the blood-brain barrier and helps renourish your body and brain at the cellular level. It also helps replace nutrients lost during chemotherapeutic and radiological treatments.
AvéULTRA (Metatrol), a fermented wheat germ product.
Selenium, vitamin D and iodine, as most cancer patients are low in these three nutrients. Since I do regular sauna therapy, I take 200 micrograms of SelenoExcell each day. (You tend to excrete selenium when sweating.) Selenium increases glutathione, an important metabolic antioxidant necessary for detoxification. It also catalyzes the conversion of thyroid hormone T4 to T3, so it can be beneficial if you have thyroid problems.
Modified citrus pectin (MCP) has been shown to reverse cancer and stop metastatic cancer. Brandt recommends the brand ecoNugenics, as this is the one that has been scientifically studied and verified to work.
Colloidal silver is a nontoxic, broad-spectrum antimicrobial therapy with no known toxicity and no known mechanism for acquired resistance.
Salicinium, a plant-based extract that inhibits production of nagalase — an enzyme produced by cancer cells — while simultaneously stimulating innate immune cells.
So as mentioned, there are many promising avenues to target cancer. Even if you’re working with a conventional oncologist, the ChemoThermia Oncology Center has published protocols your oncologist could make use of, regardless of where you live. If your oncologist isn’t willing to integrate these alternative strategies into your care regimen, you may want to consider finding a new doctor.
Originally published by: By Dr. Mercola at https://articles.mercola.com/sites/articles/archive/2017/07/25/chemotherapy-spreading-cancer.aspx?utm_source=facebook.com&utm_medium=referral&utm_content=facebookmercola_ranart&utm_campaign=20181007_chemotherapy-spreading-cancer&fbclid=IwAR1_QSRot3NmbJ0SmGLkFzRYTrksEv-XZwqi_Pt-LT2pZy1i239kHXTZqHg
Yolanda Ng was on the cusp of a full time job as a pediatric nephrologist at Providence Sacred Heart Children’s Hospital in Spokane, Washington, in the summer of 2014. She was going through the motions of onboarding at the hospital—filling out paperwork and finalizing her new position. Then she took a drug test, and it came back positive for cannabis use.
A few months prior, Ng had started to take a few drops from a cannabis-infused tincture that her friend recommended to help with menstrual cramps for a few days every month when she had her period. She tells me that it was such a small amount that she’d had no concerns about giving the requisite urine sample. Weed was already decriminalized in Washington at the time, and Ng says she had never used cannabis at work or before seeing patients.
But when the positive result came back, her supervisor said it was protocol to report her to the state’s physician health program, an organization tasked with protecting the public from unsafe medical practice. What followed was a costly and messy process of legal proceedings, suspended licenses, mandatory rehab, and regulatory middlemen—a process that pushed Ng to decide to leave the field altogether.
Now Ng’s story is another cautionary tale, adding to a growing number from medical professionals facing repercussions for using medical and recreational cannabis in the 23 states where it has been decriminalized. As the country continues to push for legalization, the lack of clarity and regulation within the medical establishment is leaving physicians in the crosshairs with little guidance and often fewer rights than other working citizens.
“The law doesn’t provide paths forward for [physicians like Ng],” says Nicole Li, an attorney who represents Ng and several other physicians who have faced similar issues as a result of both authorized medical and adult cannabis use. “Resolving the situation is going to require a political solution prompted by political pressure.”
Cases like Ng’s have cropped up across the country. There’s the neurosurgery resident in California who said she smoked weed on her days off. Or one of Li’s current clients in Washington who was only reported and tested when a patient complained about him after he refused to prescribe unnecessary opioids. Physician Paul Bregman in Colorado lost his medical license after he used marijuana as a treatment for bipolar disorder.
There are no specific laws that govern what a physician can and cannot do when it comes to cannabis. It’s widely accepted that a doctor cannot legally practice if his or her work is compromised by any drug—be it opioids, alcohol, or weed. But marijuana poses a specific challenge since the substance can stay in your system, and show up on drug tests, for up to a month after use. There is no way to distinguish between someone who smoked a joint in the morning before work and one who did so three weeks ago on a weekend.
Sometimes the rules around whether or not a doctor can use cannabis depends on the workplace, not the state. Micah Matthews, deputy executive and legislative director for the Washington Medical Commission, the state licensing agency, says that hospitals or clinics that accept federal dollars often have to comply with federal, not state, regulations. And under the US law, marijuana is still a Schedule I—i.e., illegal—drug.
“An employer may not have a problem with recreational use,” he says, “but if they accept federal money, as all hospitals tend to do, that creates some requirements for continued funding should cannabis use be discovered.”
The grey area, however, is not just about what is permitted. It’s also about who determines what happens to physicians who are found using cannabis. This task often falls to physician health programs, semi-voluntary organizations that are meant to direct physicians to rehab or report dangerous behavior. State licensing boards, like the one in Washington, often defer to these organizations to evaluate the physicians and recommend a course of action.
Physician health programs are controversial in the medical community, and have been criticized for forcing doctors into unnecessary treatment. There’s also the chance that these programs have a financial interest in sending physicians to costly treatment centers. “They’re pursuing our clients when there are dangerous doctors out there,” Li says, referring to physicians who put their patients’ safety at risk.
When psychiatrist Michael Alpert in Cambridge, Massachusetts, created a Change.org petition to protect doctors who use marijuana safely, the petition was directed at the Federation of State Physician Health Programs, which oversees the state programs. (Full disclosure: I know Alpert socially).
When I reached out to Chris Bundy, the director of Washington’s physician health program, he told me that his organization tries to address and rehabilitate doctors so that they don’t have their licenses revoked. He also emphasizes that the organization believes that regular cannabis use (which he defined as at least weekly) leads to cognitive impairment, and shouldn’t be used by doctors, especially since it is federally illegal.
“How would we know or define safe limits for physicians?” he says. “The danger is the assumption that most people have that getting drunk or high on Sunday won’t impact practice performance on Monday.”
There is a dearth of research on the long-term use of cannabis, and we still don’t know if using the drug has permanent impact on cognitive functioning in adults. But Bundy says the program would never make a decision about referral for evaluation, treatment or monitoring based only on the frequency of cannabis use. Instead, he says it has to be evaluated in the context of the other clinical information available. (Bundy didn’t comment on any specific cases.)
Doctors have spoken out against the state programs and their treatment of doctors in the past, saying the programs are not looking out for physicians like Ng. “Mandating people go for evaluations at physician health programs solely on the basis of a marijuana test is ridiculous,” says J. Wesley Boyd, a physician and associate professor of psychiatry at Harvard Medical School. “The fact that the state board of medicine in Washington state went along with that is appalling.”
In Ng’s case, the physician health program she was referred to conducted an interview, determined they couldn’t make a conclusion, and referred her to Hazelden Betty Ford Foundation Center, an addiction program, for a $5000, three-day evaluation. And while the psychologist and psychiatrist determined she wasn’t at risk, Ng tells me that one of the program’s counselors decided she had “severe substance abuse” and that her marijuana use had permanently impacted her brain.
They then recommended that she enter a three-month inpatient rehabilitation program at the same center, which would have required her to pay $50,000. When she didn’t comply, she was reported to the Washington Medical Quality Assurance Commission. “There were some people who legitimately needed to be there,” she says. “I don’t understand why I qualified.”
The misunderstanding and lack of research around cannabis use can have severe repercussions on a physician’s career, not to mention their well-being. Li says that none of the clients she’s currently representing had been reported for threatening a patient’s safety. But even then, some of their names appeared in local media, stating that they were reported for using illegal drugs.
“Physicians call me from across the country—they don’t know what kind of lawyer they need. There’s shame and stigma around it,” Li says. “The amount of suicide talk is alarming.”
Meanwhile, Ng, now living in California, says she wants to leave her past, and the stress of her three-year ordeal, behind. After hearing the requirements for probation—working every day, and remaining 100 miles away from the original hospital—she hung up her white coat entirely and is now working as an interior designer.
Originally published at: https://tonic.vice.com/en_us/article/vbknb4/doctors-using-legal-weed-suspended